- Systems Medicine
- Logical Modelling
- Bioinformatics
- Cell Biology
I’m studying a master degree in biotechnology at the Norwegian University of Science and Technology(NTNU). I have specialised within systems medicine due to my interest in the combination of bioinformatics and personalised medicine and all the possibilities that these areas hold. I’m particularly interested in the re-purposing of currently existing medicines.
My Project:
Title: Extension and Modification of a Psoriasis Keratinocyte Logical Model for the Representation of Keratinocyte Carcinomas
The aim of the project is to extend and modify the keratinocyte logical model of psoriasis made by Eirini Tsirvouli to represent keratinocyte carcinomas, specifically basal cell carcinoma (BCC). The model extension is based on the identification of signaling pathways with aberrant activity in BCC through analysis of genomics and transcriptomics data. In addition, perturbation of the model with drugs and drug combinations will be performed.
Supervisors:
Martin Kuiper – IBI, Berit Johansen – IBI, Felicity Ashcroft – IBI, Eirini Tsirvouli – IBI