The DrugLogics Initiative

The DrugLogics initiative comprises a number of different subprojects, all geared towards the development
of personalised medicine, or precision medicine

Colosys

Using computer models to predict drug resistance in colon cancer

Crossover Research 2.0

Well constructed Knowledge Commons

DrugLogics

Rational development of anti-cancer combinations

Research on the cell’s function in normal and diseased states has produced large amounts of knowledge. Modelling the behaviour of these cells and predicting how they will respond to changes in the environment and to drugs in particular, now requires the use of computational tools.

This new field of “Systems Medicine”, as many predict, will enable us to use digital simulations to select the best fitted treatment for individual patients, and enable the development of “personalised medicine”.

Systems Medicine requires cooperation of scientists from many different backgrounds, who together develop and integrate various technologies and approaches. Our goal is to use a knowledge-based approach and build integrated models of genes, proteins and other cellular components. Combined with the relational network that links these components, this produces computer models that can predict the cell’s behaviour and how they will respond to particular drugs and drug combinations. Further development of this approach may result in a software platform that could support doctors in the hospital to offer tailor-made therapy to patients.

Project description here.

COST is supported by the EU Framework Programme Horizon 2020
NTNU Health